Tuesday, May 27, 2008

Dr. Jindra's PNAS

Last year, Konopova B and Jindra M. published a paper titled as "Juvenile hormone resistance gene Methoprene-tolerant controls entry into metamorphosis in the beetle Tribolium castaneum" in Proc Natl Acad Sci U S A. 2007 May 30. This paper was considered as a breakthrough of JH action research.

In the abstract , they wrote, "Here we show that impaired function of the Met ortholog TcMet renders Tribolium resistant to the effects of ectopic JH and, in a striking contrast to Drosophila, causes early-stage beetle larvae to undergo precocious metamorphosis".

So their data seems to support that Met protein is a stong putative JH receptor. Are we close to dig JH receptor out in the near 5~10 years?

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